Not all well-differentiated cutaneous squamous cell carcinomas are equal: Tumors with disparate biologic behavior have differences in protein expression via digital spatial profiling

Matthew Vesely; Sandra Martinez-Morilla; Jeff R Gehlhausen; Jennifer M McNiff; Peter G Whang; David Rimm; Christine J Ko

doi:10.1016/j.jaad.2022.03.057

Not all well-differentiated cutaneous squamous cell carcinomas are equal: Tumors with disparate biologic behavior have differences in protein expression via digital spatial profiling

J Am Acad Dermatol. 2022 Sep;87(3):695-698. doi: 10.1016/j.jaad.2022.03.057. Epub 2022 Apr 6.

Authors

Matthew Vesely¹, Sandra Martinez-Morilla², Jeff R Gehlhausen¹, Jennifer M McNiff³, Peter G Whang⁴, David Rimm⁵, Christine J Ko⁶

Affiliations

¹ Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut.
² Boehringer Ingelheim, Ridgefield, Connecticut.
³ Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut; Department of Pathology, Yale University School of Medicine, New Haven, Connecticut.
⁴ Department of Orthopaedic Surgery, Yale University School of Medicine, New Haven, Connecticut.
⁵ Department of Pathology, Yale University School of Medicine, New Haven, Connecticut.
⁶ Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut; Department of Pathology, Yale University School of Medicine, New Haven, Connecticut. Electronic address: Christine.ko@yale.edu.

PMID: 35398219
DOI: 10.1016/j.jaad.2022.03.057

No abstract available

Keywords: atypical squamous proliferation; dermatopathology; keratoacanthoma; protein expression; skin cancer; spatial profiling; squamous cell carcinoma.

MeSH terms

Biological Products*
Carcinoma, Squamous Cell* / pathology
Humans
Immunohistochemistry
Keratoacanthoma* / pathology
Skin Neoplasms* / pathology

Substances

Biological Products