Balancing the View of C1q in Transplantation: Consideration of the Beneficial and Detrimental Aspects

Raneem Khedraki; Hirotsugu Noguchi; William M Baldwin 3rd

doi:10.3389/fimmu.2022.873479

Balancing the View of C1q in Transplantation: Consideration of the Beneficial and Detrimental Aspects

Front Immunol. 2022 Mar 24:13:873479. doi: 10.3389/fimmu.2022.873479. eCollection 2022.

Authors

Raneem Khedraki^{1

2}, Hirotsugu Noguchi¹, William M Baldwin 3rd^{1

2}

Affiliations

¹ Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, United States.
² Department of Biological, Geological, and Environmental Sciences, Cleveland State University, Cleveland, OH, United States.

No abstract available

Keywords: B cells; C1q; antibody-mediated rejection; complement; donor specific antibodies; pattern recognition receptor; tissue resident macrophages.

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Complement C1q*
Graft Rejection / prevention & control
Isoantibodies*

Substances

Isoantibodies
Complement C1q

Publication types

MeSH terms

Substances

Grants and funding