Catheter-directed thrombolysis for massive deep vein thrombosis in an adolescent with severe antithrombin deficiency

Søren Thorgaard Bønløkke; Maria Arvad Serifi; Torben Stamm Mikkelsen; Anne-Mette Hvas

doi:10.1002/ccr3.5681

Catheter-directed thrombolysis for massive deep vein thrombosis in an adolescent with severe antithrombin deficiency

Clin Case Rep. 2022 Apr 26;10(4):e05681. doi: 10.1002/ccr3.5681. eCollection 2022 Apr.

Authors

Søren Thorgaard Bønløkke^{1

2}, Maria Arvad Serifi³, Torben Stamm Mikkelsen^{2

4}, Anne-Mette Hvas^{1

2}

Affiliations

¹ Department of Clinical Biochemistry Aarhus University Hospital Aarhus Denmark.
² Department of Clinical Medicine Aarhus University Aarhus Denmark.
³ Department of Radiology Kolding Hospital Kolding Denmark.
⁴ Department of Pediatrics Aarhus University Hospital Aarhus Denmark.

Abstract

In this case report we describe a case of massive deep vein thrombosis in an adolescent. The case was complicated by severe antithrombin deficiency caused by a previously unreported mutation. We discuss the use of catheter directed thrombolysis and (F)Xa inhibitors in children and adolescents.

Keywords: cardiovascular disorders; hematology; pediatrics and adolescent medicine.

Publication types

Case Reports