Heterotopic ossification (HO) designates a bone tissue formation within an atypical anatomical location and is commonly diagnosed in patients whom have suffered major traumas. The following case report presents a non-traumatic source of HO. A causality is deduced between the HO formation and an important inflammatory reaction originating from a Coronavirus infection. In contrast to other studies not only is the source non traumatic but the HO formation is unilateral. In systemic inflammatory reactions vigilance towards HO should be enhanced especially in patients treated during prolonged periods of time in intensive care units (ICU).