Pulmonary Infections in People Living with HIV

Tomás Franquet; Pere Domingo

doi:10.1016/j.rcl.2022.01.008

Pulmonary Infections in People Living with HIV

Radiol Clin North Am. 2022 May;60(3):507-520. doi: 10.1016/j.rcl.2022.01.008.

Authors

Tomás Franquet¹, Pere Domingo²

Affiliations

¹ Department of Diagnostic Radiology, Hospital de la Santa Creu i Sant Pau, Universidad Autónoma de Barcelona, Carrer Sant Quintí, 89, Barcelona 08041, Spain. Electronic address: tfranquet@santpau.cat.
² Department of Infectious Diseases, Hospital de la Santa Creu i Sant Pau, Barcelona, Universidad Autónoma de Barcelona, Carrer Sant Quintí, 89, Barcelona 08041, Spain; Institut de Recerca Biomèdica del Hospital de Sant Pau, Carrer Sant Quintí, 77, Barcelona 08041, Spain.

PMID: 35534134
DOI: 10.1016/j.rcl.2022.01.008

Abstract

Despite the development of combination antiretroviral therapy (cART) infections continue to cause significant morbidity and mortality among people living with HIV (PLWH). Pulmonary infections with Streptococcus pneumoniae, Haemophilus influenza, and Staphylococcus aureus remain common. One-third of PLWH worldwide are infected with tuberculosis and the infection manifests at any stage of HIV infection. Fungal infection is usually confined to PLWH unaware of their HIV infection until immunosuppression is advanced or those choosing to discontinue cART. The importance of viral infections has diminished since wide availability of cART; however, mortality from COVID-19 in PLWH may remain greater than in the non-HIV population.

Keywords: Chest radiography; Computed tomography; Infection; People living with HIV; Thoracic imaging.

Publication types

Review

MeSH terms

COVID-19*
HIV Infections* / complications
HIV Infections* / epidemiology
Humans