Contemporary Management of Refractory Angina

Interv Cardiol Clin. 2022 Jul;11(3):279-292. doi: 10.1016/j.iccl.2022.03.002.

Abstract

Refractory angina (RA) is defined as chest pain caused by coronary ischemia in patients on maximal medical therapy and is not amenable to revascularization despite advanced coronary artery disease (CAD). The long-term prognosis has improved with optimal medical therapy including risk factor modification. Still, patients are left with major impairment in quality of life and have high resource utilization with limited treatment options. We review the novel invasive and noninvasive therapies under investigation for RA.

Keywords: Angina; Coronary artery disease; Microvascular.

Publication types

  • Review
  • Research Support, N.I.H., Extramural

MeSH terms

  • Angina Pectoris / diagnosis
  • Angina Pectoris / therapy
  • Coronary Artery Disease* / complications
  • Coronary Artery Disease* / surgery
  • Humans
  • Myocardial Ischemia*
  • Quality of Life
  • Risk Factors