Ocular manifestations in Kindler syndrome

Indian J Ophthalmol. 2022 Jul;70(7):2585-2587. doi: 10.4103/ijo.IJO_791_22.

Abstract

We aimed describe the chronic ocular sequelae of Kindler syndrome. All cases of Kindler syndrome with ocular involvement that presented to a tertiary eye care center were included. Three cases of Kindler syndrome with ocular changes were reviewed. Case 1 (10 years, female) had recurrent epithelial breakdown with severe dry eye and corneal opacity secondary to keratitis. Case 2 (28 years, male) had symblepharon , ocular surface keratinization , and severe dry eye. Case 3 (16 years , female ) had partial limbal stem cell deficiency with dry eye. All cases were treated with topical lubricants, short course of low-potency steroids and immuno-modulators. Attention must be paid to the eye in addition to the oro-an-genital mucosa to avoid longterm ocular sequelae.

Keywords: Dry eye; Steven Johnson syndrome; kindler syndrome; limbal stem cell deficiency.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Blister*
  • Child
  • Disease Progression*
  • Epidermolysis Bullosa
  • Eye
  • Eye Diseases* / etiology
  • Face
  • Female
  • Humans
  • Male
  • Periodontal Diseases*
  • Photosensitivity Disorders* / complications
  • Photosensitivity Disorders* / diagnosis

Supplementary concepts

  • Poikiloderma of Kindler