Comprehensiveness of Testing Among Herpes Simplex Virus Infected Infants: A Multicenter Cohort Study

Christopher M Pruitt; Lise E Nigrovic; Stephen B Freedman; Stuart A Bradin; Sarah J Curtis; Todd W Lyons; Aaron S Miller; Pamela J Okada; Suzanne M Schmidt; David Schnadower; Joanna E Thomson; Andrea T Cruz

doi:10.1097/INF.0000000000003634

Comprehensiveness of Testing Among Herpes Simplex Virus Infected Infants: A Multicenter Cohort Study

Pediatr Infect Dis J. 2022 Oct 1;41(10):851-853. doi: 10.1097/INF.0000000000003634. Epub 2022 Jul 7.

Authors

Affiliations

¹ From the Department of Pediatrics, Medical University of South Carolina, Charleston, South Carolina.
² Division of Emergency Medicine, Department of Pediatrics, Boston Children's Hospital, Boston, Massachusetts.
³ Departments of Pediatrics and Emergency Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta.
⁴ Department of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan.
⁵ Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta.
⁶ Department of Pediatrics, Saint Louis University School of Medicine, St. Louis, Missouri.
⁷ Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas.
⁸ Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
⁹ Department of Pediatrics, Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, Ohio.
¹⁰ Department of Pediatrics, Baylor College of Medicine, Houston, Texas.

PMID: 35797706
DOI: 10.1097/INF.0000000000003634

Abstract

Despite clear testing recommendations for herpes simplex virus (HSV) infection in infants, few data exist on the comprehensiveness of HSV testing in practice. In a 23-center study of 112 infants with confirmed HSV disease, less than one-fifth had all recommended testing performed, highlighting the need for increased awareness of and adherence to testing recommendations for this vulnerable population.

Publication types

Multicenter Study
Research Support, Non-U.S. Gov't

MeSH terms

Cohort Studies
Herpes Simplex* / diagnosis
Herpes Simplex* / epidemiology
Humans
Infant
Simplexvirus*