The Current State of Care for Black and Hispanic Inflammatory Bowel Disease Patients

Julia J Liu; Bincy P Abraham; Paula Adamson; Edward L Barnes; Kelly A Brister; Oriana M Damas; Sarah C Glover; Kimberly Hooks; Ana Ingram; Gilaad G Kaplan; Edward V Loftus; Dermot P B McGovern; Melodie Narain-Blackwell; Florence-Damilola Odufalu; Sandra Quezada; Vonda Reeves; Bo Shen; Thaddeus S Stappenbeck; Latonia Ward

doi:10.1093/ibd/izac124

The Current State of Care for Black and Hispanic Inflammatory Bowel Disease Patients

Inflamm Bowel Dis. 2023 Feb 1;29(2):297-307. doi: 10.1093/ibd/izac124.

Authors

Julia J Liu¹, Bincy P Abraham², Paula Adamson¹, Edward L Barnes³, Kelly A Brister⁴, Oriana M Damas⁵, Sarah C Glover⁶, Kimberly Hooks⁷, Ana Ingram⁷, Gilaad G Kaplan⁸, Edward V Loftus⁹, Dermot P B McGovern¹⁰, Melodie Narain-Blackwell⁷, Florence-Damilola Odufalu¹¹, Sandra Quezada¹², Vonda Reeves¹³, Bo Shen¹⁴, Thaddeus S Stappenbeck¹⁵, Latonia Ward⁷

Affiliations

¹ Division of Gastroenterology, Morehouse School of Medicine, Atlanta, GA, USA.
² Division of Gastroenterology and Hepatology, Houston Methodist Academic Institute, Houston, TX, USA.
³ Division of Gastroenterology and Hepatology, UNC School of Medicine, Chapel Hill, NC, USA.
⁴ Department of Surgery, University of Mississippi Medical Center, Jackson, MS, USA.
⁵ Division of Gastroenterology and Hepatology, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.
⁶ Division of Gastroenterology and Hepatology, University of Mississippi Medical Center, Jackson, MS, USA.
⁷ Color of Crohn's and Chronic Illness, Glenarden, MD, USA.
⁸ Division of Gastroenterology and Hepatology, Department of Medicine and Community Health Sciences, University of Calgary, Calgary, AB, Canada.
⁹ Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.
¹⁰ F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
¹¹ Division of Gastroenterology and Liver Diseases, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
¹² Division of Gastroenterology and Hepatology, University of Maryland, College Park, College Park, MD, USA.
¹³ GI Associates and Endoscopy Center, Jackson, MS, USA.
¹⁴ Inflammatory Bowel Disease Center, NewYork-Presbyterian Hospital/Columbia University Irving Medical Center, New York, NY, USA.
¹⁵ Department of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.

Abstract

Research on the care of inflammatory bowel disease (IBD) patients has been primarily in populations of European ancestry. However, the incidence of IBD, which comprises Crohn's disease and ulcerative colitis, is increasing in different populations around the world. In this comprehensive review, we examine the epidemiology, clinical presentations, disease phenotypes, treatment outcomes, social determinants of health, and genetic and environmental factors in the pathogenesis of IBD in Black and Hispanic patients in the United States. To improve health equity of underserved minorities with IBD, we identified the following priority areas: access to care, accurate assessment of treatment outcomes, incorporation of Black and Hispanic patients in therapeutic clinical trials, and investigation of environmental factors that lead to the increase in disease incidence.

Keywords: disparity; outcomes; pathogenesis.

Plain language summary

In this comprehensive review, we examine the epidemiology, clinical presentations, disease phenotypes, treatment outcomes, social determinants of health, and genetic and environment factors in the pathogenesis of IBD in Black and Hispanic patients in the United States.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Black or African American
Colitis, Ulcerative* / epidemiology
Crohn Disease* / therapy
Hispanic or Latino
Humans
Incidence
Inflammatory Bowel Diseases* / complications
Inflammatory Bowel Diseases* / epidemiology
Inflammatory Bowel Diseases* / therapy

Grants and funding

K23 DK117054/DK/NIDDK NIH HHS/United States