The shifting prevalence of asthma and allergic disease in US children

Ann Allergy Asthma Immunol. 2022 Oct;129(4):481-489. doi: 10.1016/j.anai.2022.06.030. Epub 2022 Jul 14.

Abstract

Background: Asthma is a chronic lung disease that affected 5 million children. Allergy is a common comorbidity of asthma. Having both conditions is associated with unfavorable health outcomes and impaired quality of life.

Objective: Purpose of this study was to assess allergy and its association with asthma by select characteristics among children to determine differences by populations.

Methods: National Health Interview Survey data (2007-2018) were used to assess asthma and allergy status, trends, and the association between allergy and asthma by select characteristics among US children (aged 0-17 years).

Results: Prevalence of asthma decreased among all children (slope [-] P < .001) and among those with allergy (slope [-] P = .002). More children had respiratory allergy (14.7%), followed by skin allergy (12.7%) and food allergy (6.4%). Prevalence of respiratory allergy significantly decreased among White non-Hispanic children (slope [-] P = .002), food allergy increased among White non-Hispanic (slope [+] P < .001) and Hispanic children (slope [+] P = .003), and skin allergy increased among Hispanic children (slope [+] P = .04). Depending on number and type, children with allergy were 2 to 8 times (skin allergy only and having all 3 allergies, respectively) more likely to have current asthma than were children without allergy. Among children with current asthma, having any allergy was significantly associated with missed school days (adjusted prevalence ratio, 1.33 [1.03-1.72]; P = .02) and taking preventive medication daily (adjusted prevalence ratio, 1.89 [1.32-2.71]; P < .001).

Conclusion: Trends in allergies across years differed by race and ethnicity. Strength of association between asthma and allergy differed by type and number of allergies, being highest among children having all 3 types of allergies. Having both asthma and allergy was associated with unfavorable asthma outcomes.

MeSH terms

  • Asthma* / complications
  • Asthma* / epidemiology
  • Child
  • Food Hypersensitivity* / complications
  • Food Hypersensitivity* / epidemiology
  • Humans
  • Prevalence
  • Quality of Life
  • Surveys and Questionnaires