Outcomes in cardiac implantable electronic device-related infective endocarditis: a systematic review of current literature

Future Cardiol. 2022 Nov;18(11):891-899. doi: 10.2217/fca-2021-0155. Epub 2022 Sep 8.

Abstract

Aim: Cardiac implantable electronic device infective endocarditis is a serious infection with poor prognosis. Materials & methods: The systematic review of the literature was conducted using searches from the various databases. We included studies published between January 2010 and June 2021. Results: A total of 35 articles met the inclusion criteria. Patients were approximately 70 years old and an average of 71.2% of patients were male. The most common presenting feature was a fever. The modified Duke criteria was used to aid diagnosis. Management entailed extraction of the cardiac implantable electronic device in 80.5% of the studies. The overall mortality rates ranged from 4 to 36%. The most frequently isolated organism was Staphylococcus aureus. Conclusion: Cardiac implantable electronic device infective endocarditis needs timely diagnosis and effective management for promising outcomes.

Keywords: artificial; bacterial; cardiac resynchronization therapy devices; endocarditis; infective endocarditis; pacemaker.

Publication types

  • Systematic Review
  • Review

MeSH terms

  • Aged
  • Defibrillators, Implantable* / adverse effects
  • Electronics
  • Endocarditis* / diagnosis
  • Endocarditis* / etiology
  • Endocarditis* / therapy
  • Endocarditis, Bacterial* / diagnosis
  • Endocarditis, Bacterial* / etiology
  • Endocarditis, Bacterial* / therapy
  • Female
  • Humans
  • Male
  • Pacemaker, Artificial* / adverse effects