How Did Zero-Markup Medicines Policy Change Prescriptions in the Eyes of Patients?-A Retrospective Quasi-Experimental Analysis

Int J Environ Res Public Health. 2022 Sep 27;19(19):12226. doi: 10.3390/ijerph191912226.

Abstract

Background: China implemented the zero-markup medicines policy to reverse the overuse of medicine in public health institutions, by changing the distorted financing mechanism, which heavily relies on revenue generated from medicines. The zero-markup medicines policy was progressively implemented in city public hospitals from 2015 to 2017.

Objective: This study is expected to generate convincing evidence with subjective measurements and contribute to a more comprehensive evaluation of the policy from both objective and subjective perspectives.

Methods: This study was based on a large patient-level dataset with a quasi-experimental design. We employed the difference-in-difference (DID) method, combined with propensity score matching methods, to estimate the causal effect of the policy in reducing overprescriptions from the patient perspective.

Results: The study estimated a statistically significant increased probability that the responded outpatients denied overprescription in their visiting hospitals. The mean interacted policy effect, in percentage points, of all observations were positive (logit DID model: 0.15, z = 10.27, SE = 0.01; PSM logit DID model: 0.15, z = 10.26, SE = 0.01; PSM logit DID hospital fixed-effect model: 0.12, z = 3.00, SE = 0.04).

Discussion: The policy might reduce overprescription in public hospitals from the patient's perspective. The patient's attitude is one aspect of a comprehensive policy evaluation. The final concrete conclusion of the policy evaluation can only be made through a systematic review of the studies with rigorous design and with both objective and subjective measurements.

Keywords: hospital; outpatient; overuse; policy effect; prescription; zero-markup medicines policy.

Publication types

  • Systematic Review

MeSH terms

  • China
  • Drug and Narcotic Control*
  • Health Policy
  • Humans
  • Policy*
  • Prescriptions
  • Retrospective Studies

Grants and funding

This research received no external funding. But this research was based on the surveys that was funded by the National Health Commission of China, National Healthcare Improvement Initiative of China [2016-2019].