Low-grade fibromyxoid sarcoma (LGFMS) is a rare tumor characterized by bland histological features and aggressive clinical course, it is a distinctive variant of fibrosarcoma with high metastasizing potential and sometimes a long interval between tumor presentation and metastasis, the most common anatomic locations of occurrence are the lower extremities, thorax, inguinal area, and upper limbs, Here, we present the case of a 29-year-old patient with a deceptively benign-appearing mass arising in the mediastinum that had been discovered on computed tomography, a biopsy under cervicotomy was performed and histopathological examination revealed low-grade fibromyxoid sarcoma. In conclusion, LGFMS can arise in the mediastinum, and physicians should consider this entity as a differential diagnosis in the presence of such mass.
Keywords: Case report; Fibromyxoid; Imaging; Mediastinum; Sarcoma.
© 2022 The Authors. Published by Elsevier Inc. on behalf of University of Washington.