Disseminated Mycobacterium Tuberculosis and IgA Nephropathy

Gordon Audley; Bianca Davidson; Erika Jones; Brendon Price; Brian Rayner; Nicola Wearne; Zibya Barday

doi:10.1155/2022/3785713

Disseminated Mycobacterium Tuberculosis and IgA Nephropathy

Case Rep Nephrol. 2022 Nov 1:2022:3785713. doi: 10.1155/2022/3785713. eCollection 2022.

Authors

Gordon Audley¹, Bianca Davidson², Erika Jones², Brendon Price³, Brian Rayner², Nicola Wearne², Zibya Barday²

Affiliations

¹ Division of General Medicine, Department of Medicine, Faculty of Health Sciences, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa.
² Division of Nephrology and Hypertension, Department of Medicine, Faculty of Health Sciences, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa.
³ Division of Anatomical Pathology, Department of Pathology, Faculty of Health Sciences, University of Cape Town/National Health Laboratory Services, Groote Schuur Hospital, Cape Town, South Africa.

Abstract

Mycobacterium tuberculosis (MTB) is an under-recognised cause of genitourinary disease. IgA nephropathy (IgAN), a leading cause of glomerulonephritis worldwide, has been described as a rare consequence of disseminated MTB infection. In this case report, we present the first case of MTB associated IgAN in Africa. Finding IgAN on kidney biopsy in an MTB endemic area should prompt a thorough investigation for MTB to increase the chance of remission of IgAN and prevent inappropriate use of immunosuppression.

Publication types

Case Reports