T cells are ready for the fight against monkeypox

Dannielle Wellington; Tao Dong

doi:10.1016/j.chom.2022.11.004

T cells are ready for the fight against monkeypox

Cell Host Microbe. 2022 Dec 14;30(12):1653-1654. doi: 10.1016/j.chom.2022.11.004.

Authors

Dannielle Wellington¹, Tao Dong²

Affiliations

¹ Chinese Academy of Medical Science Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
² Chinese Academy of Medical Science Oxford Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK. Electronic address: tao.dong@ndm.ox.ac.uk.

Abstract

In this issue of Cell Host & Microbe, Grifoni et al. provide reassuring evidence that the majority of epitopes induced by vaccinia virus vaccines are conserved in monkeypox virus and can elicit memory T cell responses, while also providing an extensive list of potential T cell epitopes.

MeSH terms

Epitopes, T-Lymphocyte
Humans
Monkeypox virus
Mpox (monkeypox)* / prevention & control
T-Lymphocytes
Vaccinia virus

Substances

Epitopes, T-Lymphocyte

Grants and funding

MC_UU_00008/11/MRC_/Medical Research Council/United Kingdom