RORγt-lineage APCs: The Aire apparent

James M Gardner; Adrian Liston

doi:10.1126/sciimmunol.ade9240

RORγt-lineage APCs: The Aire apparent

Sci Immunol. 2022 Dec 23;7(78):eade9240. doi: 10.1126/sciimmunol.ade9240. Epub 2022 Dec 16.

Authors

James M Gardner^{1

2}, Adrian Liston³

Affiliations

¹ Diabetes Center, University of California San Francisco, San Francisco, CA 94143, USA.
² Department of Surgery, University of California San Francisco, San Francisco, CA 94143, USA.
³ Immunology Programme, Babraham Institute, Babraham Research Campus, Cambridge, CB22 3AT UK.

PMID: 36525506
DOI: 10.1126/sciimmunol.ade9240

Abstract

Recent studies shed light on new populations and potential roles of Aire⁺ and RORγt⁺ antigen-presenting cells-including unique subsets with surprising properties-in immune homeostasis and host-microbe interactions.

Publication types

Review

MeSH terms

Antigen-Presenting Cells*
Nuclear Receptor Subfamily 1, Group F, Member 3* / genetics

Substances

Nuclear Receptor Subfamily 1, Group F, Member 3