Safety of Surgery Among Asymptomatic SARS-CoV-2 PCR-Positive Patients: A Single-Center Retrospective Cohort Study

World J Surg. 2023 Mar;47(3):573-577. doi: 10.1007/s00268-023-06891-z. Epub 2023 Jan 13.

Abstract

Background: Screening with SARS-CoV-2 PCR tests is recommended for all patients undergoing surgery under general anesthesia, and elective surgery is deferred for positive patients. This study evaluated the outcomes of asymptomatic PCR-positive patients who underwent general anesthesia and surgery.

Methods: Patient data were collected from the hospital records of patients who underwent surgery between January 2021 and May 2022. Asymptomatic patients with a positive PCR test between 7 days before and 5 days after surgery were compared with controls. The cases were propensity score-matched with a 1:2 ratio to the controls. All-cause in-hospital mortality was the primary outcome of the study.

Results: A total of 217 asymptomatic PCR-positive patients were matched to 434 controls. In multivariate analysis, PCR-positive test results were not associated with mortality (log(OR) (95%CIs), p; 0.86 (- 0.13, 1.9), 0.09). Age and ASA score (>3) were the most significant risk factors associated with mortality.

Conclusion: This study found that surgery among asymptomatic PCR-positive patients was not associated with increased mortality.

MeSH terms

  • COVID-19 Testing
  • COVID-19* / diagnosis
  • Elective Surgical Procedures
  • Humans
  • Polymerase Chain Reaction
  • Retrospective Studies
  • SARS-CoV-2*