LED-based Hyperspectral Endoscopic Imaging

Proc SPIE Int Soc Opt Eng. 2022 Jan-Feb:11954:1195408. doi: 10.1117/12.2609023. Epub 2022 Mar 2.

Abstract

Hyperspectral endoscopy can offer multiple advantages as compared to conventional endoscopy. Our goal is to design and develop a real-time hyperspectral endoscopic imaging system for the diagnosis of gastrointestinal (GI) tract cancers using a micro-LED array as an in-situ illumination source. The wavelengths of the system range from ultraviolet to visible and near infrared. To evaluate the use of the LED array for hyperspectral imaging, we designed a prototype system and conducted ex vivo experiments using normal and cancerous tissues of mice, chicken, and sheep. We compared the results of our LED-based approach with our reference hyperspectral camera system. The results confirm the similarity between the LED-based hyperspectral imaging system and the reference HSI camera. Our LED-based hyperspectral imaging system can be used not only as an endoscope but also as a laparoscopic or handheld devices for cancer detection and surgery.

Keywords: FPGA; Hyperspectral imaging; cancer; endoscopy; handheld device; laparoscope; micro-LED; surgery.