Should we expect weight changes in people with HIV and a reported weight gain only by switching antiretroviral therapy?

New Microbiol. 2023 Feb;46(1):65-67.

Abstract

Weight gain following the initiation or the switch of antiretroviral therapy (ART) is well documented and mainly associated with some of the most recent drugs, such as integrase strand transfer inhibitors and tenofovir alafenamide. However, limited data have been published on weight trends in ART-experienced people living with HIV (PLWH) with a long exposure to HIV infection and antiretroviral drugs. In our study, we assessed changes in weight after switching ART among PLWH who reported weight gain under a previous regimen.

Keywords: Antiretroviral Therapy; Body Mass Index; Drug Switching; HIV; Weight Gain.

MeSH terms

  • Anti-Retroviral Agents / therapeutic use
  • HIV Infections* / drug therapy
  • Humans
  • Weight Gain

Substances

  • Anti-Retroviral Agents