Primary breast angiosarcoma: A case report

Front Surg. 2023 Feb 17:9:966792. doi: 10.3389/fsurg.2022.966792. eCollection 2022.

Abstract

Background: Primary breast angiosarcoma (PBA) is a rare sarcoma, accounting for only 0.04% of all breast malignancies, with a difficult diagnosis and a poor prognosis. Mastectomy is the standard treatment, and the role of adjuvant treatment (chemotherapy and/or radiotherapy following surgery) remains uncertain with very few studies.

Case presentation: We report the case of a 17-year-old female patient who presented with a right breast lump that had rapidly increased in size and was hemorrhaging. She was diagnosed with breast angiosarcoma by needle biopsy and pathological evaluation. However, the mass showed a quick tendency to bleed during biopsies. After that, we performed angiography and tumor vascular embolization. The patient underwent a mastectomy followed by adjuvant chemotherapy.

Conclusion: Tumor vascular embolization reduced the surgical risk of PBA with hemorrhage complications. Postoperative therapeutic roles still need further exploration and verification.

Keywords: DSA (digital subtraction angiography); breast angiosarcoma; case report; chemotherapy; radiotherapy; surgery.

Publication types

  • Case Reports

Grants and funding

This work was supported by the New Xiangya Talent Project of the Third Xiangya Hospital of Central South University (Grant number: 20180301).