[Characteristics and research progress on the role of intestinal fungi in chronic liver disease]

Zhonghua Gan Zang Bing Za Zhi. 2022 Nov 20;30(11):1285-1288. doi: 10.3760/cma.j.cn501113-20201030-00588.
[Article in Chinese]

Abstract

At present, a large number of studies have revealed that intestinal bacteria play a very complex role in benign liver diseases, while there is relatively little research on intestinal fungi. As part of the gut microbiome, intestinal fungi are insignificant in numbers compared with intestinal bacteria, but the impact of intestinal fungi on human health and diseases cannot be ignored. This paper summarizes the characteristics and research progress of intestinal fungi in patients with alcoholic liver disease, nonalcoholic fatty liver disease, viral hepatitis and liver cirrhosis, so as to provide basis of reference and ideas for the further research on the diagnosis and treatment of intestinal fungi in benign liver diseases.

目前已有大量研究揭示肠道细菌在肝脏良性疾病中发挥着十分复杂的作用,而对肠道真菌的研究却相对较少。作为肠道微生物的一部分,肠道真菌的数量相比于肠道细菌可以忽略,但肠道真菌对人体健康与疾病存在的影响却不容忽视。现总结目前酒精性肝病、非酒精性脂肪性肝病、病毒性肝炎和肝硬化患者肠道真菌的特点及其研究进展,为肠道真菌在肝脏良性疾病诊断和治疗方面的进一步研究提供参考依据与思路。.

Publication types

  • English Abstract

MeSH terms

  • Fungi
  • Humans
  • Intestines
  • Liver Cirrhosis / microbiology
  • Liver Diseases, Alcoholic*
  • Non-alcoholic Fatty Liver Disease* / therapy