Effect of ultrasound-supported wound debridement in subjects with diabetic foot ulcers: A meta-analysis

Int Wound J. 2023 Sep;20(7):2618-2625. doi: 10.1111/iwj.14133. Epub 2023 Mar 11.

Abstract

A meta-analysis study to assess the effect of ultrasound-supported wound debridement (USSD) in subjects with diabetic foot ulcer (DFU). A comprehensive literature examination till January 2023 was implemented and 1873 linked studies were appraised. The picked studies contained 577 subjects with DFUs in the studies' baseline, 282 of them were using USSD, 204 were using standard care, and 91 were using a placebo. Odds ratio (OR) in addition to 95% confidence intervals (CIs) were used to calculate the consequence of USSD in subjects with DFUs by the dichotomous styles and a fixed or random effect model. The USSD applied to DFU caused a significantly higher wound healing rate compared with the standard care (OR, 3.08; 95% CI, 1.94-4.88, P < .001) with no heterogeneity (I2 = 0%) and the placebo (OR, 7.61; 95% CI, 3.11-18.63, P = .02) with no heterogeneity (I2 = 0%). The USSD applied to DFUs caused a significantly higher wound healing rate compared with the standard care and the placebo. Though precautions should be taken when commerce with the consequences as all of the picked studies for this meta-analysis was with low sample sizes.

Keywords: diabetic foot ulcer; standard of care; ultrasound-supported wound debridement; wound healing rate.

Publication types

  • Meta-Analysis

MeSH terms

  • Debridement
  • Diabetes Mellitus*
  • Diabetic Foot* / diagnosis
  • Diabetic Foot* / therapy
  • Humans
  • Odds Ratio
  • Ultrasonography
  • Wound Healing