Coronavirus Disease-2019 in Pregnancy

Jose Rojas-Suarez; Jezid Miranda

doi:10.1016/j.ccm.2022.11.015

Coronavirus Disease-2019 in Pregnancy

Clin Chest Med. 2023 Jun;44(2):373-384. doi: 10.1016/j.ccm.2022.11.015. Epub 2022 Nov 23.

Authors

Jose Rojas-Suarez¹, Jezid Miranda²

Affiliations

¹ Intensive Care and Obstetric Research Group (GRICIO), Department of Obstetrics and Gynecology, Universidad de Cartagena, Colombia. Electronic address: jrojass@unicartagena.edu.co.
² Intensive Care and Obstetric Research Group (GRICIO), Department of Obstetrics and Gynecology, Universidad de Cartagena, Colombia; Department of Obstetrics and Gynecology, Maternal-Fetal Medicine Division, Centro Hospitalario Serena del Mar, Cartagena, Colombia.

Abstract

Coronavirus disease-2019 (COVID-19) infection during pregnancy is associated with severe complications and adverse effects for the mother, the fetus, and the neonate. The frequency of these outcomes varies according to the region, the gestational age, and the presence of comorbidities. Many COVID-19 interventions, including oxygen therapy, high-flow nasal cannula, and invasive mechanical ventilation, are challenging and require understanding physiologic adaptations of pregnancy. Vaccination is safe during pregnancy and lactation and constitutes the most important intervention to reduce severe disease and complications.

Keywords: Acute respiratory distress syndrome; COVID-19; Perinatal outcomes; Pregnancy; SARS-CoV-2.

Publication types

Review

MeSH terms

COVID-19*
Female
Humans
Infant, Newborn
Noninvasive Ventilation*
Oxygen Inhalation Therapy
Pregnancy
Pregnancy Outcome
Respiration, Artificial
SARS-CoV-2