Contemporary surgical management of colorectal cancer in Lynch syndrome

J Surg Oncol. 2023 Jun;127(8):1259-1263. doi: 10.1002/jso.27318.

Abstract

Lynch syndrome is the most common hereditary colorectal cancer syndrome. Although the current literature has been supportive of extended resections in certain Lynch syndrome patients with colon cancer. This article reviews the recent data on the topic and raises questions about the importance of homogenous high-quality prospective data to establish the accurate risk of cancer and future risk of metachronous cancer in the setting of all these risk reduction interventions.

Keywords: Lynch; colon; prevention; rectal; risk.

Publication types

  • Review

MeSH terms

  • Colonic Neoplasms*
  • Colorectal Neoplasms, Hereditary Nonpolyposis* / genetics
  • Colorectal Neoplasms, Hereditary Nonpolyposis* / surgery
  • Humans
  • Neoplastic Syndromes, Hereditary*
  • Prospective Studies
  • Risk Reduction Behavior