Anti-hypertensive prescription practices in private hospitals in Malaysia: a prospective, non-interventional, observational study

Med J Malaysia. 2023 May;78(3):350-356.

Abstract

Introduction: In managing hypertension, monotherapy and sometimes a combination of more than one agent are used to achieve blood pressure (BP) control. The objective of this prospective, observational, multi-centre study was to assess the level of BP control in patients receiving one or more anti-hypertensive drugs in private medical centres in Malaysia according to the treatment regimens (monotherapy, free drug combinations and single pill combinations).

Materials and methods: Data were collected through medical records and interview sessions with patients on current pharmacotherapy for hypertension management at baseline and 2-3 months later. Results are expressed as mean ± SD for continuous data and as frequencies and percentages for categorical data.

Results: Among 182 recruited patients, 89 (49%) achieved BP control by the end of the study. Majority (62/89) patients were on single-pill (monotherapy or SPC) antihypertensives. Majority (63/89) required more than two antihypertensives to achieve BP control.

Conclusion: Both SPC and free drug combination antihypertensives reduced BPs, but physicians preferred SPC to improve BP control and increase treatment compliance.

Publication types

  • Observational Study
  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antihypertensive Agents* / adverse effects
  • Antihypertensive Agents* / therapeutic use
  • Blood Pressure
  • Drug Combinations
  • Hospitals, Private
  • Humans
  • Hypertension* / drug therapy
  • Malaysia
  • Prospective Studies

Substances

  • Antihypertensive Agents
  • Drug Combinations