Symptom Cluster Profiles in Adults with Chronic Obstructive Pulmonary Disease and Insomnia

West J Nurs Res. 2023 Sep;45(9):789-799. doi: 10.1177/01939459231184709. Epub 2023 Jun 28.

Abstract

Background: People with chronic obstructive pulmonary disease (COPD) and insomnia may experience multiple symptoms that can affect physical function, but little research has focused on symptom clusters in this population.

Objectives: This study aimed to identify subgroups of people with COPD and insomnia based on a pre-specified symptom cluster and determine whether physical function differed in the subgroups.

Methods: This secondary data analysis included 102 people with insomnia and COPD. Latent profile analysis classified subgroups of individuals sharing similar patterns of five symptoms: insomnia, dyspnea, fatigue, anxiety, and depression. Multinomial logistic regression and multiple regression determined factors associated with the subgroups and whether physical function differed among them.

Results: Three groups of participants were identified based on the severity of all five symptoms: low (Class 1), intermediate (Class 2), and high (Class 3). Compared to Class 1, Class 3 showed lower self-efficacy for sleep and for COPD management and more dysfunctional beliefs and attitudes about sleep. Class 3 showed more dysfunctional beliefs and attitudes about sleep than Class 2. Class 1 showed significantly better physical function than Classes 2 and 3.

Conclusions: Self-efficacy for sleep and for COPD management and dysfunctional beliefs and attitudes about sleep were associated with class membership. As physical function differed among subgroups, interventions to improve self-efficacy for sleep and for COPD management and minimize dysfunctional beliefs and attitudes about sleep may reduce symptom cluster severity, in turn enhancing physical function.

Keywords: chronic obstructive pulmonary disease; insomnia; latent profile analysis; self-efficacy; sleep; symptom cluster.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Dyspnea / complications
  • Humans
  • Pulmonary Disease, Chronic Obstructive* / complications
  • Sleep
  • Sleep Initiation and Maintenance Disorders* / complications
  • Syndrome