The temporal and bi-directional relationship between physical activity and sleep in ambulatory children with cerebral palsy

Anke Gerritsen; Raquel Y Hulst; Ilse M van Rijssen; Joyce Obeid; Sigrid Pillen; Jan Willem Gorter; Olaf Verschuren

doi:10.1080/09638288.2023.2232720

The temporal and bi-directional relationship between physical activity and sleep in ambulatory children with cerebral palsy

Disabil Rehabil. 2023 Jul 9:1-7. doi: 10.1080/09638288.2023.2232720. Online ahead of print.

Authors

Anke Gerritsen^{1

2}, Raquel Y Hulst¹, Ilse M van Rijssen¹, Joyce Obeid³, Sigrid Pillen^{4

5}, Jan Willem Gorter^{1

3

6}, Olaf Verschuren¹

Affiliations

¹ Center of Excellence for Rehabilitation Medicine, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University and De Hoogstraat Rehabilitation, Utrecht, The Netherlands.
² Faculty of Health and Physical Activity, Saxion University of Applied Sciences, Enschede, the Netherlands.
³ CanChild, Department of Pediatrics, McMaster University, Hamilton, Canada.
⁴ Kinderslaapexpert BV (Pediatric Sleep Expert LTd), Mook, The Netherlands.
⁵ Department of Electrical Engineering, Technical University Eindhoven, Eindhoven, The Netherlands.
⁶ Department of Rehabilitation, Physical Therapy Science and Sports, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, The Netherlands.

PMID: 37424307
DOI: 10.1080/09638288.2023.2232720

Abstract

Purpose: Exploring the temporal and bi-directional relationship between device-based measures of physical activity and sleep in ambulatory children with cerebral palsy (CP).

Materials and methods: 24-hour activity data were collected from children with CP (n = 51, 43% girls, mean age (range); 6.8 (3-12) years; Gross Motor Function Classification System levels I to III). Nocturnal sleep parameters and daily physical activity were measured for seven consecutive days and nights using ActiGraph GT3X accelerometers. Linear mixed models were constructed to explore the relationships between sleep and activity.

Results: Light and moderate-to-vigorous activity were negatively associated with sleep efficiency (SE) (resp. p = 0.04, p = 0.010) and total sleep time (TST) (resp. p = 0.007, p = 0.016) the following night. Sedentary time was positively associated with SE and TST the following night (resp. p = 0.014, p = 0.004). SE and TST were positively associated with sedentary time (resp. p = 0.011, p = 0.001) and negatively with moderate-to-vigorous physical activity (resp. p < 0.001, p = 0.002) the following day. Total bedtime and TST were negatively associated with light physical activity (resp. p = 0.046, p = 0.004) the following day.

Conclusions: The findings from this study suggest that ambulatory children with CP may not sleep better after physical activity, and vice versa, indicating that the relationship is complex and needs further investigation.

Keywords: Cerebral palsy; accelerometry; children; physical activity; sleep.

Plain language summary

The use of device-based accelerometry is a feasible method to measure 24-hour activity patterns with sleep and physical activity in ambulatory children with cerebral palsy.The relationships between sleep and physical activity in children with cerebral palsy are not as expected based on patterns shown in peers with typical development.Interventions for sleep in children with cerebral palsy require a holistic approach, focusing on daily physical activity patterns and relevant child- and contextual factors.