1 Richard Gray, MSc, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom; Matt Seymour, MD, St James's University Hospital, Leeds, United Kingdom; Laura Magill, PhD and Kelly Handley, PhD, University of Birmingham Clinical Trials Unit, Birmingham, United Kingdom; Philip Quirke, MD and Nick West, MD, Division of Pathology and Data Analytics, School of Medicine, University of Leeds, Leeds, United Kingdom; and Dion Morton, MD, University Hospital Birmingham, Birmingham, United Kingdom.