Electron microscopic definition of surface antigens of group B Streptococcus

J Infect Dis. 1979 Feb;139(2):147-51. doi: 10.1093/infdis/139.2.147.

Abstract

Strains representing each of the five serologically distinct types of group B Streptococcus and variant strain 090R, which is devoid of type-specific polysaccharide, were studied by electron microscopy after incubation with various ferritin-conjugated antibodies. Ferritin-conjugated types Ia, II and III antibodies localized on homologous cells in a pattern that defines the capsular location of the type Ia, II, and III polysaccharide antigen. Type Ib and Ic cells have surface antigens to which ferritin-labeled antibodies to both capsular polysaccharide and a common surface protein attach.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Antigen-Antibody Reactions
  • Antigens, Surface / analysis*
  • Ferritins
  • Immunologic Techniques
  • Polysaccharides, Bacterial / analysis
  • Polysaccharides, Bacterial / immunology
  • Rabbits
  • Streptococcus agalactiae / immunology*
  • Streptococcus agalactiae / ultrastructure

Substances

  • Antigens, Surface
  • Polysaccharides, Bacterial
  • Ferritins