Counting steps

Nat Synth. 2023 Jan;2(1):6-8. doi: 10.1038/s44160-022-00204-3. Epub 2023 Jan 2.

Abstract

The use of step count as a metric of synthetic efficiency carries opportunities and challenges. Here, proposals are made to standardize what constitutes a synthetic step and how steps are counted. These proposals may be beneficial in the holistic evaluation of published synthetic routes.