Genetic characterization of Klebsiella pneumoniae carbapenemase -producing Klebsiella pneumoniae isolates with different susceptibility to ceftazidime/avibactam in patients with blood-stream infections

Clin Microbiol Infect. 2023 Dec;29(12):1610-1612. doi: 10.1016/j.cmi.2023.08.024. Epub 2023 Aug 31.
No abstract available

Keywords: Ceftazidime/avibactam reduced susceptibility; Ceftazidime/avibactam resistance; KPC-Klebsiella pneumoniae blood-stream infections; Porin mutations; WGS.

Publication types

  • Letter

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Bacterial Proteins / genetics
  • Ceftazidime* / pharmacology
  • Drug Combinations
  • Humans
  • Klebsiella
  • Klebsiella Infections* / microbiology
  • Klebsiella pneumoniae / genetics
  • Microbial Sensitivity Tests
  • beta-Lactamases / genetics

Substances

  • Ceftazidime
  • carbapenemase
  • avibactam
  • beta-Lactamases
  • Bacterial Proteins
  • Drug Combinations
  • Anti-Bacterial Agents