Nuclear protein of the testis (NUT) midline carcinoma (NMC) is a rare malignant epithelial tumor that typically occurs in the midline regions such as the head, neck, and mediastinum. This tumor is characterized by rapid development, aggressive growth, and strong invasiveness. Due to its short duration, most patients are diagnosed at advanced stages, often leading to rapid mortality. Although reports on pulmonary NUT carcinoma are uncommon, this article presents a case of pulmonary NUT carcinoma in which the patient repeatedly expectorated bronchial casts and tumor tissue. Additionally, a comprehensive review of relevant literature from recent years is provided to enhance understanding of this disease.
睾丸核蛋白（nuclear protein of the testis，NUT）中线癌（NUT midline carcinoma，NMC）是一种罕见的恶性上皮肿瘤，通常发生在头颈部和纵隔等人体中线位置。其临床特点为发展迅速、生长迅猛，并具有强烈的侵袭性。由于其病程短暂，多数患者在晚期才被发现，往往导致迅速的死亡。肺源性NUT癌的报道较为罕见，本文报道1例反复多次咯出支气管管型状凝血块及肿瘤组织的肺源性NUT癌，并结合相关文献，以期加深临床对本病的认识。.