Dual-Energy Computed Tomography Applications in Lung Cancer

Zachary J Hartley-Blossom; Subba R Digumarthy

doi:10.1016/j.rcl.2023.06.001

Dual-Energy Computed Tomography Applications in Lung Cancer

Radiol Clin North Am. 2023 Nov;61(6):987-994. doi: 10.1016/j.rcl.2023.06.001. Epub 2023 Aug 4.

Authors

Zachary J Hartley-Blossom¹, Subba R Digumarthy²

Affiliations

¹ Division of Thoracic Imaging and Intervention, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.
² Division of Thoracic Imaging and Intervention, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA. Electronic address: sdigumarthy@mgh.harvard.edu.

PMID: 37758365
DOI: 10.1016/j.rcl.2023.06.001

Abstract

This article examines the intrathoracic applications for dual-energy computed tomography (DECT), focusing on lung cancer. The topics covered include the image data sets, methods for iodine quantification, and clinical applications. The applications of DECT are to differentiate benign and malignant lung nodules, determining the grade of lung cancer and expression of ki-67 expression. Iodine quantification has role in assessment of treatment response in both the primary tumor and nodal metastases.

Keywords: Clinical application; Dual-energy CT; Iodine concentration; Iodine maps; Lung cancer; Thoracic imaging; Treatment response.

Publication types

Review

MeSH terms

Humans
Iodine*
Lung Neoplasms* / diagnostic imaging
Radiography, Dual-Energy Scanned Projection* / methods
Tomography, X-Ray Computed / methods

Substances

Iodine