This Topic on the "Application of Graphene-Based Materials", which consists of a total of twenty-six articles, including two review articles, written by research groups of experts in the field, considers the most recent research and trends on the synthesis and characterization of graphene-based materials, including nanohybrids, intended for a vast array of high-demanding technological applications, namely batteries/fuel cells, aerogels, laser technology, sensors, electronic/magnetic devices, catalysts, etc [...].