Stevens-Johnson syndrome and COVID-19: a case report with suspected multisystem inflammatory syndrome in children (MIS-C)

Mohsen Ebrahimi; Seyed Ali Aghapour; Azam Rashidbaghan; Mahshid Mazandarani

doi:10.1097/MS9.0000000000001087

Stevens-Johnson syndrome and COVID-19: a case report with suspected multisystem inflammatory syndrome in children (MIS-C)

Ann Med Surg (Lond). 2023 Sep 22;85(11):5641-5644. doi: 10.1097/MS9.0000000000001087. eCollection 2023 Nov.

Authors

Mohsen Ebrahimi¹, Seyed Ali Aghapour¹, Azam Rashidbaghan¹, Mahshid Mazandarani¹

Affiliation

¹ Neonatal and Children's Health Research Center, Golestan University of Medical Sciences, Gorgan, Iran.

Abstract

Introduction and importance: Symptoms similar to diseases such as Stevens-Johnson syndrome (SJS) and multisystemic inflammatory syndrome in children (MIS-C) were reported in pediatric coronavirus infections.

Case presentation: Here, we present a 4-year-old girl with coronavirus disease 2019 (COVID-19), an earlier diagnosis of SJS, and a final diagnosis of MIS-C.

Clinical discussion: Unlike the negative PCR test for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the positive serological test confirmed COVID-19.

Conclusion: The monitoring of this case indicated that higher coronavirus infection can delay immune reaction and cause symptoms similar to SJS.

Keywords: MIS-C; Stevens–Johnson syndrome; case report; coronavirus infection.