Computed Tomography-Derived Physiology Assessment: State-of-the-Art Review

Robert D Safian

doi:10.1016/j.ccl.2023.07.004

Computed Tomography-Derived Physiology Assessment: State-of-the-Art Review

Cardiol Clin. 2024 Feb;42(1):101-123. doi: 10.1016/j.ccl.2023.07.004.

Author

Robert D Safian¹

Affiliation

¹ The Lucia Zurkowski Endowed Chair, Center for Innovation & Research in Cardiovascular Diseases (CIRC), Department of Cardiovascular Medicine, Oakland University, William Beaumont School of Medicine, William Beaumont University Hospital, Royal Oak, MI 48073, USA. Electronic address: robert.safian@beaumont.edu.

PMID: 37949532
DOI: 10.1016/j.ccl.2023.07.004

Abstract

Coronary computed tomography angiography (CCTA) and CCTA-derived fractional flow reserve (FFRCT) are the best non-invasive techniques to assess coronary artery disease (CAD) and myocardial ischemia. Advances in these technologies allow a paradigm shift to the use of CCTA and FFRCT for advanced plaque characterization and planning myocardial revascularization.

Keywords: Coronary artery disease; Coronary computed tomography angiography; Fractional flow reserve; Myocardial ischemia; Planning revascularization; Plaque characterization.

Publication types

Review

MeSH terms

Coronary Angiography / methods
Coronary Artery Disease* / diagnostic imaging
Coronary Vessels / diagnostic imaging
Fractional Flow Reserve, Myocardial* / physiology
Humans
Myocardial Ischemia* / diagnostic imaging
Predictive Value of Tests
Tomography, X-Ray Computed