Abnormal Myocardial Deformation Despite Normal Ejection Fraction in Hutchinson-Gilford Progeria Syndrome

J Am Heart Assoc. 2024 Feb 6;13(3):e031470. doi: 10.1161/JAHA.123.031470. Epub 2024 Jan 31.

Flemming J Olsen^{1

2

3}, Tor Biering-Sørensen³, Fatima Lunze¹, Sheila M Hegde⁴, Steven D Colan^{1

2}, Rachel Ehrbar⁵, Joseph Massaro⁵, Alessandra M Ferraro¹, David M Harrild^{1

2}, Monica E Kleinman^{6

7

2}, Leslie B Gordon^{7

8}, Ashwin Prakash^{1

2}

¹ Department of Cardiology Boston Children's Hospital Boston MA USA.
² Department of Pediatrics Harvard Medical School Boston MA USA.
³ Department of Cardiology Copenhagen University Hospital-Herlev and Gentofte Hellerup Denmark.
⁴ Department of Medicine, Cardiovascular Medicine Brigham and Women's Hospital Boston MA USA.
⁵ Department of Mathematics and Statistics Boston University, and Harvard Clinical Research Institute Boston MA USA.
⁶ Department of Critical Care Medicine Boston Children's Hospital Boston MA USA.
⁷ Department of Anesthesia Boston Children's Hospital Boston MA USA.
⁸ Department of Pediatrics Hasbro Children's Hospital, and Warren Alpert Medical School of Brown University Providence RI USA.

No abstract available

Keywords: deformation; echocardiography; progeria; strain.

MeSH terms