Sarcoid heart disease and imaging

Jian Liang Tan; Gregory E Supple; Saman Nazarian

doi:10.1016/j.hroo.2023.11.012

Sarcoid heart disease and imaging

Heart Rhythm O2. 2023 Nov 19;5(1):50-59. doi: 10.1016/j.hroo.2023.11.012. eCollection 2024 Jan.

Authors

Jian Liang Tan¹, Gregory E Supple¹, Saman Nazarian¹

Affiliation

¹ Electrophysiology Section, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.

Abstract

Cardiac sarcoidosis (CS) can mimic any cardiomyopathy due to its ability to manifest with a variety of clinical presentations. The exact prevalence of CS remains unknown but has been reported ranging from 2.3% to as high as 29.9% among patients presenting with new onset cardiomyopathy and/or atrioventricular block. Early and accurate diagnosis of CS is often challenging due to the nature of disease progression and lack of diagnostic reference standard. The current diagnostic criteria for CS are lacking in sensitivity and specificity. Here, we review the contemporary role of advanced imaging modalities such as cardiac magnetic resonance imaging and positron emission tomography/computed tomography imaging in diagnosing and prognosticating patients with CS.

Keywords: Cardiac magnetic resonance imaging; Cardiac sarcoidosis; PET; Sarcoid; Sudden cardiac death.

Publication types

Review