Strategies for treating acute pain in patients with opioid dependence: a scoping review protocol

BMJ Open. 2024 Feb 7;14(2):e080740. doi: 10.1136/bmjopen-2023-080740.

Abstract

Introduction: People who are dependent on opioids experience acute pain similar to other individuals. However, treating acute pain in these patients renders unique challenges such as opioid-induced hyperalgesia, opioid tolerance, withdrawal and stigma from healthcare providers. Thus, it is crucial to identify effective strategies for treating acute pain in this population and to highlight gaps in knowledge to create a high standard of care. The main objective of the proposed scoping review is to identify current strategies for treating the acute pain in individuals with opioid dependence or use disorder.

Methods and analysis: MEDLINE via the PubMed interface, Embase and Cochrane Central, Web of Science: Conference Proceedings Citation Index and Google Scholar will be searched. Forward and backward citation searching of the final included studies will also be conducted. Two independent reviewers will screen the titles and abstracts of sources, review and assess relevant full-text studies and extract data. Data will be presented in a diagram and will contribute to a qualitative thematic analysis.

Ethics and dissemination: Data will be gathered from publicly accessible sources, so ethics approval is not necessary. The results will be disseminated through a peer-reviewed journal and reported at conferences related to addiction medicine.

Trial registration number: 10.17605/OSF.IO/BG6SJ.

Keywords: adult palliative care; pain management; patient-centered care.

MeSH terms

  • Acute Pain* / drug therapy
  • Analgesics, Opioid / therapeutic use
  • Drug Tolerance
  • Humans
  • Opioid-Related Disorders*
  • Peer Review
  • Research Design
  • Review Literature as Topic

Substances

  • Analgesics, Opioid