Advancing Artificial Intelligence Integration Into the Pathology Workflow: Exploring Opportunities in Gastrointestinal Tract Biopsies

Lab Invest. 2024 May;104(5):102043. doi: 10.1016/j.labinv.2024.102043. Epub 2024 Feb 29.

Abstract

This review aims to present a comprehensive overview of the current landscape of artificial intelligence (AI) applications in the analysis of tubular gastrointestinal biopsies. These publications cover a spectrum of conditions, ranging from inflammatory ailments to malignancies. Moving beyond the conventional diagnosis based on hematoxylin and eosin-stained whole-slide images, the review explores additional implications of AI, including its involvement in interpreting immunohistochemical results, molecular subtyping, and the identification of cellular spatial biomarkers. Furthermore, the review examines how AI can contribute to enhancing the quality and control of diagnostic processes, introducing new workflow options, and addressing the limitations and caveats associated with current AI platforms in this context.

Keywords: artificial intelligence; digital pathology; gastrointestinal pathology; machine learning.

Publication types

  • Review

MeSH terms

  • Artificial Intelligence*
  • Biopsy / methods
  • Gastrointestinal Diseases / diagnosis
  • Gastrointestinal Diseases / pathology
  • Gastrointestinal Tract* / metabolism
  • Gastrointestinal Tract* / pathology
  • Humans
  • Workflow*