[Discussion on the application status and method improvement of gas chromatography in occupational health inspection standards in China]

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2024 Mar 20;42(3):213-217. doi: 10.3760/cma.j.cn121094-20221017-00496.
[Article in Chinese]

Abstract

As a rapid, accurate and efficient analytical technique, gas chromatography is widely used in the detection of volatile organic compounds and inorganic small molecule toxins, and it is the main analytical method in the national testing standards for occupational health. The existing effective national standards of gas chromatography for the detection of some substances have low column efficiency, high toxicity of reagents, poor correlation of the standard curve and low desorption efficiency and other problems, some of which can be solved through method improvement. At the same time, with the use of new materials and new processes, new types of toxic substances are emerging, and there are still many occupational disease hazards of limited value without supporting detection methods, gas chromatography can be applied to the detection of some toxic substances to better complement the vacancy of China's occupational health detection methods. This paper analyzes the current situation of the application of gas chromatography in occupational health testing standards, discusses the improvement of some of these methods, and helps to promote the application and development of gas chromatography in occupational health testing.

气相色谱法作为一种快速、准确、高效的分析技术,广泛应用于挥发性有机化合物和无机小分子类毒物的检测,是职业卫生国家检测标准中的主要分析方法。现行有效的国家职业卫生标准中的气相色谱法对于部分物质的检测存在柱效低、试剂毒性大、标准曲线相关性差和解吸效率低等问题,部分物质的检测可以通过方法改进得以解决。同时,随着新材料、新工艺的使用,新型毒物层出不穷,仍有许多有职业接触限值的危害因素还没有配套的检测方法,而气相色谱法可以应用于部分毒物的检测,更好地补充我国职业卫生检测方法的空缺。本文对气相色谱法在职业卫生检测标准中的应用现状进行分析,对其中部分方法的改进加以探讨,为气相色谱法在职业卫生检测中的应用和发展提供支持。.

Keywords: Chromatography, gas; National standard detection method; New toxicants; Occupational health; Volatile organic compounds; Workplace.

Publication types

  • English Abstract

MeSH terms

  • Air Pollutants, Occupational* / analysis
  • China
  • Chromatography, Gas / methods
  • Occupational Health*
  • Workplace

Substances

  • Air Pollutants, Occupational