A multi-centre randomised control trial of directly observed therapy to promote medication adherence in paediatric heart transplant recipients

Cardiol Young. 2024 Apr 12:1-4. doi: 10.1017/S1047951124000775. Online ahead of print.

Abstract

Medication non-adherence remains a significant challenge for adolescent heart transplant recipients. Building on the success of a pilot intervention study, herein we describe the protocol for a follow-up randomised control trial using mobile video directly observed therapy, featuring several innovations, to promote medication adherence in a multi-centre sample of adolescent heart transplant patients.

Keywords: Paediatric heart transplantation; adolescent; mHealth; medication adherence.