Surgery for ulcerative colitis

Semin Pediatr Surg. 2024 Apr;33(2):151404. doi: 10.1016/j.sempedsurg.2024.151404. Epub 2024 Mar 28.

Abstract

Ulcerative colitis (UC) has a more severe presentation and rapid progression in pediatric patients, resulting in a greater need for surgical intervention compared to adults. Though medical management of UC has advanced with new biologic therapies, surgery continues to play an important role when disease progresses in the form of worsened or persistent symptoms, hemodynamic instability, or sepsis. The goals of surgical management are to restore intestinal continuity with a functional pouch when possible. While the literature has been growing regarding studies of pediatric patients with UC, high level of evidence studies are limited and most recommendations are based on adult studies. Similar to adults, pediatric patients who have ileal pouches created require surveillance for recurrent disease and cancer surveillance. Unique issues for pediatric patients include monitoring of growth and appropriate transition to adult care after adolescence. This review includes indications for surgical management, overview of staged surgical approaches, and the technical details of the three-stage approach.

Keywords: Acute severe colitis; Ileal pouch-anal anastomosis; Inflammatory bowel disease; Pediatric surgery; Ulcerative colitis.

Publication types

  • Review

MeSH terms

  • Child
  • Colitis, Ulcerative* / diagnosis
  • Colitis, Ulcerative* / surgery
  • Colitis, Ulcerative* / therapy
  • Colonic Pouches
  • Humans
  • Proctocolectomy, Restorative* / methods