Surgically induced necrotizing scleritis (SINS): Is it a standalone condition or a variant of necrotizing scleritis?

Kowsigan Magesan; Parthopratim D Majumder; Mamta Agarwal; Amala E George; Vinita Nair; Sudha K Ganesh; Jyotirmay Biswas

doi:10.4103/IJO.IJO_2724_23

Surgically induced necrotizing scleritis (SINS): Is it a standalone condition or a variant of necrotizing scleritis?

Indian J Ophthalmol. 2024 Apr 16. doi: 10.4103/IJO.IJO_2724_23. Online ahead of print.

Authors

Kowsigan Magesan¹, Parthopratim D Majumder¹, Mamta Agarwal², Amala E George¹, Vinita Nair¹, Sudha K Ganesh¹, Jyotirmay Biswas¹

Affiliations

¹ Department of Uvea, Medical and Vision, Research Foundations, Sankara Nethralaya, Nungambakkam, Chennai, Tamil Nadu, India.
² Department of Cornea and Uvea, Medical and Vision, Research Foundations, Sankara Nethralaya, Nungambakkam, Chennai, Tamil Nadu, India.

PMID: 38622865
DOI: 10.4103/IJO.IJO_2724_23

Abstract

Purpose: To report the clinical pattern of surgically induced necrotizing scleritis (SINS) in a tertiary eye care center in Southern India.

Methods: Retrospective analysis of all SINS cases visiting the uveitis clinic of a tertiary eye institute between January 2009 and April 2019.

Results: In total, 15 patients with a median age of 65 (IQR:52-70) years were included in the study. Male (53%) predominance was noted, and SINS was unilateral (100%) in all cases. Most (87%) of the patients developed SINS after a single surgical procedure, with a median onset period of 251 (IQR:127-1095) days. None of these patients had any evidence of systemic association. Ocular hypertension (n = 3, 20%), and cataract (n = 5, 33%) were the most common complications. When compared with a cohort of patients with idiopathic necrotizing scleritis, the index study did not find any statistically significant difference between SINS and idiopathic scleritis.

Conclusion: SINS is idiopathic necrotizing scleritis rather than an independent entity of scleritis.