Changes in Cognitive Function Following Bariatric Surgery: An Updated Systematic Review

Obes Surg. 2024 Apr 26. doi: 10.1007/s11695-024-07235-z. Online ahead of print.

Abstract

Since a previous systematic review published in 2016, there have been further studies investigating the association of changes in cognitive function following bariatric surgery. All studies since the original review that reported at least one element of cognitive function before and after bariatric surgery were eligible. A total of 137 additional studies were identified; 13 were included in addition to the 18 studies previously. Almost all studies reported improvements in at least one domain. Most revealed improvements were limited to a few domains and were not universal. Further findings investigated cognitive function improvement in relation to procedure choice, and mental health or quality of life post-surgery. Further high-powered studies are still necessary, but these findings support the impact of bariatric surgery on cognitive function in obesity.

Keywords: Alzheimer’s disease; Bariatric surgery; Cognition; Cognitive function; Dementia; Gastric band; Gastric bypass; Gastric surgery; Metabolic surgery; Roux-en-Y gastric bypass; Sleeve gastrectomy.

Publication types

  • Review