Cholangiocarcinoma: Epidemiology and Imaging-Based Review

R I Med J (2013). 2024 May 2;107(5):43-48.

Abstract

Cholangiocarcinoma (CCA) is a rare cancer of the bile duct epithelium, and in the last few decades its incidence rate has been increasing. It is associated with a high mortality rate due to late diagnosis and its aggressive nature. Many risk factors have been identified; some are more common in certain regions than others. CCA can be classified according to its anatomical location or macroscopic growth pattern, the latter being most helpful for imaging interpretation. Clinical features can vary from obstructive-like symptoms to nonspecific symptoms, such as weight loss and malaise. Imaging, specifically MRI/MRCP, is crucial in diagnosing CCA, staging, and treatment planning. Surgery with chemotherapy is the mainstay treatment option, and other palliative treatment options exist for those who have unresectable disease.

Keywords: Biliary Tract; CT; Cholangiocarcinoma; Imaging; MRCP; MRI; Ultrasound.

Publication types

  • Review

MeSH terms

  • Bile Duct Neoplasms* / diagnosis
  • Bile Duct Neoplasms* / diagnostic imaging
  • Bile Duct Neoplasms* / epidemiology
  • Bile Duct Neoplasms* / therapy
  • Bile Ducts, Intrahepatic / diagnostic imaging
  • Bile Ducts, Intrahepatic / pathology
  • Cholangiocarcinoma* / diagnosis
  • Cholangiocarcinoma* / diagnostic imaging
  • Cholangiocarcinoma* / epidemiology
  • Cholangiocarcinoma* / therapy
  • Humans
  • Magnetic Resonance Imaging
  • Risk Factors