Breast Cancer

Cold Spring Harb Perspect Med. 2024 May 1:a041729. doi: 10.1101/cshperspect.a041729. Online ahead of print.

Abstract

Breast cancer kills hundreds of thousands of people every year. Rapid progress over the past two decades has increased our understanding of the genetic and environmental risk factors for disease. It has also shed light on drivers of tumor progression and the molecular landscape underpinning tumor heterogeneity, as well as the role of the microenvironment and the immune system. These strides forward should lead to more effective and tailored therapies for early- and late-stage patients.