Subcutaneous phaeohyphomycosis due to Phaeoacremonium venezuelense: The first clinical case report in Costa Rica

Med Mycol Case Rep. 2024 Apr 27:44:100650. doi: 10.1016/j.mmcr.2024.100650. eCollection 2024 Jun.

Abstract

Phaeoacremonium is a genus of dematiaceous fungi that rarely causes human infections. We describe a case of subcutaneous infection in a 70-year-old diabetic man with lesions on the dorsum of the one foot. The agent was isolated, and for the final identification we performed matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) and DNA sequencing. After diagnosis, the patient underwent curettage of the cyst and received 100mg of Itraconazole, twice daily for 6 months. Clinical resolution of the lesion was observed after treatment. This is the first case of infection by Phaeoacremonium venezuelense reported in Costa Rica.

Keywords: Dematiaceus fungi; Phaeoacremonium venezuelense; Phaeohyphomycosis; Phaeohyphomycotic cyst; Subcutaneous nodule.

Publication types

  • Case Reports