Tall-columnar glandular cells in SurePath™ liquid-based cytology Pap sample: Learning from mimics/pitfalls

Nalini Gupta; Vanita Jain; Radhika Srinivasan; Tulika Singh

doi:10.1111/cyt.13385

Tall-columnar glandular cells in SurePath™ liquid-based cytology Pap sample: Learning from mimics/pitfalls

Cytopathology. 2024 May 7. doi: 10.1111/cyt.13385. Online ahead of print.

Authors

Nalini Gupta¹, Vanita Jain², Radhika Srinivasan¹, Tulika Singh³

Affiliations

¹ Department of Cytology and Gynaecologic Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
² Department of Obstetrics and Gynaecology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
³ Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

PMID: 38712698
DOI: 10.1111/cyt.13385

Abstract

We offer a comprehensive depiction of the cytomorphological characteristics of lobular endocervical glandular hyperplasia (LEGH) as observed in SurePath™ liquid-based cytology (LBC), subsequently confirmed on cone biopsy. Lobular endocervical glandular hyperplasia (LEGH), a precursor to gastric-type adenocarcinoma (GAE) of the endocervix, is rare and reports of it in cervical cytology are scarce. We provide a thorough description of the cytomorphological features of LEGH observed in SurePath™ liquid-based cytology (LBC), later confirmed by cone biopsy. To the best of our knowledge, this is the first report documenting cytology of LEGH in LBC of a Pap sample.

Keywords: Pap sample; gastric type adenocarcinoma endocervix; intestinal metaplasia; liquid‐based cytology; lobular endocervical glandular hyperplasia.

Publication types

Case Reports