Osteolytic lesions as a presenting sign of acute myeloid leukemia: a case report

Jingqian Zhang; Shidai Mu; Li Cai; Lisha Ai; Yaohui Wu

doi:10.3389/fonc.2024.1364266

Osteolytic lesions as a presenting sign of acute myeloid leukemia: a case report

Front Oncol. 2024 May 1:14:1364266. doi: 10.3389/fonc.2024.1364266. eCollection 2024.

Authors

Jingqian Zhang^#^{1

2}, Shidai Mu^#¹, Li Cai¹, Lisha Ai¹, Yaohui Wu¹

Affiliations

¹ Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
² Key Lab of Molecular Biological Targeted Therapies of the Ministry of Education, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

^# Contributed equally.

Abstract

Osteolytic lesions are infrequently observed in adult patients with acute myeloid leukemia (AML). This report details the case of a 66-year-old male patient who presented with myeloid sarcoma (MS), osteolytic lesion and pancytopenia. Effective treatments were delayed due to diagnostic challenges and the rapid progression of the disease. It is essential to consider AML in the differential diagnosis when faced with a patient presenting osteolytic lesions and pancytopenia.

Keywords: acute myeloid leukemia; case report; diagnosis; myeloid sarcoma; osteolytic lesions; pancytopenia.

Publication types

Case Reports

Grants and funding

The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was supported by the National Natural Science Foundation of China (No.81000211 and No.81500172) and Nature Science Foundation of Hubei Province (No.2020CFB790).